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The finding that 12 weeks showed a larger effect size (SMD: 1.08) than 2124 weeks (SMD: 0.64) does not mean treatment becomes ineffective after 12 weeks

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Because the vial is more dilute, the same 2 mg dose now needs 0.8 mL, which equals 80 units on a U-100 syringe

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Cassoli JS, Guest PC, Malchow B, Schmitt A, Falkai P, Martins-de-Souza D

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