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Targeting Nrf2-mediated oxidative stress response in traumatic brain injury: therapeutic perspectives of phytochemicals

10.1111/j.2042-7158.2011.01367.x 136 SunG.-D.LiC.-Y.CuiW.-P.GuoQ.-Y.DongC.-Q.ZouH.-B.et al (2015)

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A typical course involves a defined run of consecutive daily injections, with the cycle repeated periodically through the year and recovery built in between cycles

However, these agents remain in early preclinical stages, requiring the optimization of tissue penetration and proteasomal degradation efficiency