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Notably, ferroptosis inhibitors or proteasome inhibitors can effectively alleviate HSV-1-associated encephalitis by inhibiting NRF2 degradation (Xu et al., 2023)

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One route involves the hydrolysis of cytoplasmic CE by neutral cholesterol esterase and the resulting free cholesterol is mobilized away from the ACAT pool (72,73) and made available for efflux via ABCA1, ABCG1, SR-BI, and aqueous diffusion (Figure 2)

But current evidence suggests that it may play an important role in maintaining optimal health and wellness

ALS patients are often advised to engage in moderate exercise and seek physical therapy to maintain muscle strength and function