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doi: 10.4239/wjd.v6.i4.548 [DOI] [PMC free article] [PubMed] [Google Scholar]

While H 2 O 2 and superoxide are certainly capable of effecting unwanted oxidations, it is the hydroxyl radical that is the key

Therefore, this review aims to summarize the regulation of metabolism on inflammatory response and oxidative stress in the pathogenesis of ARDS, explain the regulatory effects of various metabolites and the mechanisms involved, and finally introduce the current potential therapeutic drugs for metabolic regulation in ARDS