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Once it reaches the last part of the small intestine, the ileum, its absorbed from the GI tract where B12 detaches from IF and joins transcobalamin to become B12 TC-II

ABSTRACT Obesity is a significant risk factor for health issues like type 2 diabetes and cardiovascular disease

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V-ATPases are critical for pH homeostasis by acidifying lysosomes and are involved in processes like macropinocytosis, autophagy, cell invasion, and cell death 27,51

An overview of the major traditional systems of medicine and their approaches to GI health is summarized in Figure 1