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While intravenous delivery can increase systemic exposure, it may also introduce complications such as abscess formation, neurovascular injury, muscle fibrosis, and persistent pain at the injection site [7, 8]

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Biochem J 453:115 Belanger M, Yang J, Petit JM, Laroche T, Magistretti PJ, Allaman I (2011) Role of the glyoxalase system in astrocyte-mediated neuroprotection