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GraphPad Prism was used to calculate the area under the curve (AUC) for both parameters with or without 5FU, and then the difference in AUC was calculated as (AUC +5FU) (AUC 5FU)

Given that COPD does not disappear when exposure to cigarette smoke is discontinued, it has been hypothesized that additional parameters, including autoimmunity or chronic infection, could also be responsible for disease progression [8]

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When any of the key ETC genes are deficient or ETC action is inhibited, the number of ROS increase, and high levels of accumulated ROS may induce ferroptosis

Meaney et al