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This patient's lack of primary gastrointestinal malignancies and presence of a parafollicular cell neoplasm make a DNA mismatch repair gene mutation unlikely

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10.1016/j.freeradbiomed.2007.12.020 107 ParienteR.BejaranoI.EspinoJ.RodrguezA

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It was these findings that paved the way for the use of mTOR inhibitors as potential therapies for mitochondrial disease (Johnson et al., 2013

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