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For example, in mouse embryonic stem cells, excess 2-OG maintains pluripotency dependent on the 2-OG/succinate ratio by increasing TET and KDM activity 45

These compounds work through independent mechanisms, meaning they can potentially be used together under physician supervision without pharmacological conflict

Kuhn V, Diederich L, Keller STC IV, Kramer CM, Lckstdt W, Panknin C, Suvorava T, Isakson BE, Kelm M, Cortese-Krott MM (2017) Red blood cell function and dysfunction: redox regulation, nitric oxide metabolism, Anemia

Glutathione actually works synergistically with Vitamin C they recycle each other

Factors such as a poor diet, environmental pollutants, and the natural process of aging can deplete our stores