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Cycloheximide inhibits protein synthesis by binding to the 60S ribosomal subunit in eukaryotic cells, blocking peptide chain elongation (Schneider-Poetsch et al., 2010)

Why do the lesions develop and then heal rather than persist indefinitely if high serum vitamin B 12 caused them to form? While it is interesting that one in ten healthy subjects injected with high dose vitamin B 12 developed acne, adds Eady, it is more significant that nine out of ten did not