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10.1016/j.neuron.2008.01.003 Neuron Summary Keywords blood-brain barrier, amino acid transport, facilitative transport, active transport, cell polarity, luminal membrane, abluminal membrane, endothelial cells Citation Zaragoz R (2020) Transport of Amino Acids Across the Blood-Brain Barrier

5 A similar trial that also included slightly older patients (age range 7-16 years) with ASD found that 24 or 12 IU oxytocin given once daily over four days did not significantly improve primary outcomes such as emotion recognition or social interaction skills in their study

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3.1.1.4 Grape seed proanthocyanidin extract (GSPE) GSPE, a natural bioactive compound from plant, exhibits great therapeutic properties through inhibiting oxidative stress and promoting mitochondrial biogenesis ( via AMPK-Sirtuin-1-PGC-1-TFAM signaling pathway ( 3.1.2 Sirtuin activators 3.1.2.1 Resveratrol Resveratrol, a natural compound extracted from the berries of Vaccinium species, can activate sirtuin-1, sirtuin-3, and sirtuin-5 (Xia et al., 2017