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For example, it has been shown to: Decrease levels of DNA damage when administered to senescence-accelerated mice [15]

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With TNFR2 playing a role in enhancing immunomodulation via regulatory T (Treg) cells and mesenchymal-derived suppressor cells, as well as having a protective effect against cardiac disease and multiple sclerosis [58], developing drugs targeting TNFR1 and TNFR2 is an avenue for reducing the side effects and enhancing the specificity of TNF- therapy

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Those with known sensitivity to copper or any component of a specific formulation should consult a dermatologist prior to use