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Cotter, N.J

10.1155/2019/9437043 127 SunX.NiuX.ChenR.HeW.ChenD.KangR.et al (2016a)

It was approved in 2023 for geographic atrophy (GA) secondary to AMD, but its current label only recommends treatment for up to 12 months

The hypoxiareperfusion cycles characteristic of PE promote excessive ROS generation through activation of xanthine oxidase and mitochondrial electron transport chain complexes I and III, contributing to vascular and placental dysfunction 13,28