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Under normoxia and high glucose availability, most acetyl-CoA is produced from glucose-derived pyruvate via pyruvate dehydrogenase and exported as citrate for lipid synthesis

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Whats Normal vs Whats Not Usually normal and temporary: Mild headaches Injection site irritation Short-term fatigue Minor water retention May require dose adjustment: Ongoing headaches Persistent swelling Repeated nausea Noticeable appetite changes Should be discussed promptly with a provider: Side effects lasting longer than two weeks Symptoms that worsen over time Anything that interferes with daily activities Who Is More Likely to Experience Side Effects