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Boivin J, et al

In addition, Ub (K48R) and K29-Ub4 further modify other K48 residues of K29-Ub4, forming a K29/K48 branched Ub chain with more than 15-mer Ub (K29/K48-Ub15 ~ )

53,54,55 Both the phosphorylation of PGD at Y481 upon EGFR activation and acetylation of PGD at K76 and K294 by acetyltransferases enhance its activation for producing NADPH in cancer cells