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Synthesis of insulin-like growth factor binding proteins and of the acid-labile subunit in primary cultures of rat hepatocytes, of Kupffer cells, and in cocultures: regulation by insulin, insulinlike growth factor, and growth hormone

Am J Clin Nutr 93:234242

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(7) Particularly in the case of continuous exposure for 24 hours, the peptide apparently led to an increase from roughly 2030 gL24 h under placebo conditions to about 120180 gL24 h with GHRP-2, implying an approximate 4- to 6-fold rise in growth hormone production