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Description

Cell Death Dis (2019) 10(12):879

M.BreaG.et al

The vitamin is composed of a corrin ring surrounding a central cobalt atom that is bound to a lower ( -axial ) and an upper ( -axial ) ligand (see Figure 1, 2 )

It requires a specific protein produced in the stomach to bind to the B12 molecule, and then specialised receptors in the lower small intestine to actually take it up into the body