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This complication can cause significant impairment in hand function and may require surgical intervention

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For an adult with documented vitamin B12 deficiency requiring a weekly intramuscular injection, how many milliliters should be drawn from a vial that contains 1000 g (1 mg) per mL?

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Vincristine caused a sharp increase in histone 3 phosphorylation at serine 10 (pS10-H3), likely due to its interference with mitotic spindle assembly, causing mitotic arrest ( Supplementary Figure S7A )