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The model of CTR: rAmy (CT-like, PDB: 7TYI) was used as the initial template for the CTR:Cagri/CagriBB complex in the CT-like conformation by replacement of the peptide

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The copolymer (C-2) in the second coating comprises 25 to 60 mol-% methacrylic acid repeating units and 40 to 75 mol-% methyl methacrylate repeating units, preferably 25 to 40 mol-% methacrylic acid repeating units and 60 to 75 mol-% methyl methacrylate repeating units