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Description

Airway-occluding mucus plugs and mortality in patients with chronic obstructive Pulmonary disease

C.Perez-GrandaM

Glutamate surges to toxic levels

When an oxidative stressor or electrophile interacts with the Keap1-Nrf2 complex, it allows for the release and subsequent nuclear accumulation of Nrf2 through a complex process of ubiquitination-inhibition, thus triggering an anti-stress response by the cell