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38 The release of lysosomal enzymes into the cytosol is dependent on the specific lysosomal enzyme cathepsin B

Patients should be encouraged to consume B12-rich foods, including: Meat, particularly liver and kidney Fish and shellfish Dairy products (milk, cheese, yoghurt) Eggs Fortified breakfast cereals and plant-based milk alternatives For patients following plant-based diets, fortified foods and supplementation become essential, as vitamin B12 is naturally found almost exclusively in animal products

At temperatures colder than 25 C, denatured RuBisCO had similar active site density (4.8 10 3 INPs mg 1 ) as native RuBisCO at 8.8 C (4.6 10 3 INPs mg 1 ) (Fig

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Upon binding to their coactivators YAP and TAZ, TEAD transcription factors regulate the transcription of target genes within the Hippo pathway [28]