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Nature Medicine 2013

When to Call 911 vs

Toxicol Lett 188:148152 Berg D, Youdim MB (2006) Role of iron in neurodegenerative disorders

It has been demonstrated that bifidobacteria regulate fat accumulation by upregulating mRNA expression of thermogenic genes and lipolytic enzymes, and inhibiting activation of lipogenic genes

To counteract this and make the drug effective for a longer time, inhibitor molecules like that in PDB entry 3gss can be administered along with the drug to inhibit the action of the enzymes