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Most clinical evidence is topical

Dinh QN, Drummond GR, Sobey CG, Chrissobolis S

On the other hand, Dayan et al

Among them, oxidative stress refers to the excessive accumulation of reactive oxygen species (ROS) that leads to the imbalance of oxidants and antioxidants, oxidative stress has the ability to lead to mitochondrial dysfunction and lysosome dysfunction, and ultimately induces neurodegenerative disease (Caspersen et al., 2005