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Daratumumab is administered by IV infusion in combination with Pd at 16 mg/kg QW for 8 weeks, Q2W in weeks 924, and Q4W from week 25, and in combination with Kd at 8 mg/kg on days 1 and 2 in week 1, followed by 16 mg/kg QW in weeks 28, Q2W in weeks 924, and Q4W from week 25 [13, 15]