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Blood samples collected after the peak of the water crisis may not indicate the actual lead levels children were exposed to, which is likely higher than the measured values

Acidosis during simultaneous use From the 1057 patients, 51 patients (4.8%) had a serum pH value of 7.35 during the period of simultaneous use, or within 48 h of discontinuation of 1 or both drugs

However, a small fraction, roughly 1%3%, escapes, generating superoxide

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The medication is not recommended during pregnancy, and women of reproductive potential should be counseled about potential risks