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MDD and sickness behavior Vegetative symptoms of melancholic depression, such as anorexia, weight loss, psychomotor retardation, sleep disorders, and anergy, are substantially and positively correlated with signs of the AP response, including increased serum haptoglobin levels and the alpha 2 globulin fraction [28, 110]

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No human dose is established

Subclinical copper insufficiency in aging brains may be more common than recognized, and GHK-Cu represents a bioavailable delivery mechanism

Age and baseline GHK levels Natural GHK production declines with age