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In contrast, AIF-3 had a full NADPH dehydrogenase activity comparable to WT AIF (Fig

Blockade of the phagocytic receptor merTK on tumor-associated macrophages enhances P2X7R-dependent STING activation by tumor-derived cGAMP

The MGBA immune links described earlier (Th17 cells, etc.) are pertinent too PD patients have been found to have increased Th17 cells in circulation, and recent research implicates gut bacteria in shaping this PD-specific immune profile [161]