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These changes may reflect not only the biochemical effects of the supplements but also possible improvements in metabolic flexibility and mitochondrial function areas increasingly linked to cardiometabolic resilience

Niacinamide: Helps improve the appearance of dullness and uneven skin tone, and supports the appearance of the skin barrier

Recently, sourdough has been used in the baking industry to produce breads with reduced usage of additives (label cleaning) [127], improved organoleptic characteristics and nutritional content [29,128]

These findings are consistent with our spatial transcriptomic analysis, which revealed a significant upregulation of GPX4 mRNA expression in patients post-treatment samples (Fig