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Slides were deparaffinized in xylene, rehydrated through a graded ethanol series, and subjected to antigen retrieval in citrate buffer (pH 6.0) using microwave heating

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Ethics declarations Ethics Approval All experiments involving animals were carried out in accordance with NIH guidelines and were approved by the University of Selcuk Animal Care and Use Committee (Protocol Number: 201828)

Bleomycin (BLM), a glycol peptide, cleaves nucleic acid in a sequence-selective manner through metal-dependent oxidative cleavage in the presence of oxygen