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Additional experimental and large-scale clinical designs with optimal dose and duration of homocysteine-lowering treatment are needed to definitively prove that homocysteine is responsible for the increased risk of cardiovascular disease, mostly of atherosclerosis

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Some of these infection-linked chronic symptoms overlap or exacerbate ones caused by conditions that can come with obesity, such as depression

For practical purposes in modern research, the terms are used interchangeably to describe the synthetic four-amino-acid chain