chac1 glutathione degradation of enhances cystine-starvation-induced necroptosis and ferroptosis in human triple negative breast cancer cells via the GCN2-eIF2α-ATF4 pathway Human CHAC1 (Glutathione-specific gamma-glutamylcyclotransferase 1)

Human CHAC1 (Glutathione specific gamma glutamylcyclotransferase 1) ELISA Kit Glutathione Peroxidase 8 Suppression by Histone Deacetylase Inhibitors Enhances Endoplasmic Reticulum Stress and Cell Death by Oxidative Stress in Hepatocellular Carcinoma Cells CHAC1: a master regulator of oxidative stress and ferroptosis in human diseases and cancers PMC Mammalian proapoptotic factor ChaC1 and its homologues function as glutamyl cyclotransferases acting specifically on glutathione EMBO Reports Springer Nature Link Identification of Juglone, a 'first in class' inhibitor of the human glutathione degrading enzyme, ChaC1, using yeast based high throughput screens bioRxiv

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