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Copper excess triggers oxidative stress (by impairing antioxidant enzymes and NO bioavailability) and disrupts Ca homeostasis, leading to endothelial dysfunction, cardiac hypertrophy, and contractile impairment

The explants were reviewed by an expert hepatic pathologist with focus on histologic fibrosis staging and microscopic features of AAH and steatohepatitis for steatosis grade, Mallory bodies, cytologic ballooning, lobular and portal inflammation, neutrophilic infiltration, bilirubinostasis, and megamitochondria

PMID: 34423400

"Neisserial Binding to CEACAM1 Arrests the Activation and Proliferation of CD4+ T Lymphocytes." Nat Immunol 3.3 (2002): 229-36

This combination of hydration and disruption of the mucin interactome sharply reduces inflammatory stresses on airway epithelia and helps to prolong cough relief, owing to the osmotic effects of the released globular proteins