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Sikiric and colleagues have proposed nitric oxide system involvement, while other groups have documented effects on VEGF receptor 2 expression, growth-hormone receptor upregulation, and dopamine pathway modulation

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When pentadecapeptide BPC 157 was given immediately after paracetamol, BPC 157 rats started to rear on hind legs and shake shortly after paracetamol application while after 10 minutes, they became sleepy, with a tottering walk, after 35 min they regained normal behavior, drank (but not excessively) and then ate and showed no behavioral abnormalities until their sacrifice ( Table 5 )