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Understanding how the active forms of these vitamins, specifically methylcobalamin and L-5-methyltetrahydrofolate (L-5-MTHF), support the body at a molecular level can provide a validating framework for managing the complex symptoms of Long COVID and ME/CFS

Other AMPs secreted by enterocytes include alpha () and beta () defensins, c-type lectins, cathelicidin, lysozyme, and intestinal alkaline phosphatases, each of which are important in limiting the colonisation and invasion of enteric pathogens (Dupont et al

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This research provides insight into how B12 impacts the gut microbiota and highlights potential consequences of disrupting microbial B12 competition/sharing through over-supplementation