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Furthermore, CKD in patients with diabetes is globally the leading cause of end-stage kidney disease and leading to increased health care cost due to renal replacement therapy [4]

Compared with background healing, treatment with GHK and RGD-GHK showed an obvious wound-healing rate of 90.9% and 95.8% at 24 h, respectively, while the control showed a rate of 36.9% at 24 h