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doi: 10.1158/0008-5472.Can-09-1947 32 GuertinDASabatiniDM

Innate immune response in rainbow trout ( Oncorhynchus mykiss ) against primary and secondary infections with Yersinia ruckeri O1

Why was the clinical trial stopped The official reasons were never disclosed

Investigators are particularly interested in determining the mechanisms by which effects observed in murine models relate to broader mammalian metabolic regulation, and whether different experimental conditions (young vs aged models, healthy vs metabolically compromised states) show differential responses to NNMT inhibition