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In chronic wounds, there is excessive secretion of inflammatory mediators, such as cytokines and matrix metalloproteinases (MMPs), which degrade growth factors and the extracellular matrix (ECM), further impairing healing

Primary conclusions emphasized no significant average group differences in neurobehavioral outcomes, but secondary and re-analyses highlighted signals in subgroups, dose-response relationships, renal biomarkers, and genetic susceptibility.

Additionally, tumor cells utilize fatty acids for the synthesis of biomembranes and crucial signaling molecules to support their own survival, invasion, metastasis, and drug resistance [96]

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Considering the non-toxic nature of B12 even in substantial quantities, we believe it is better to err on the side of caution