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An imbalance of glutathione is present in many pathologies including cancer, neurodegenerative disorders, cystic fibrosis (CF), HIV and aging

In contrast to NIK inhibitors that target a pathway-proximal step that simultaneously blocks signals from multiple NIK-activating receptors and poses a higher safety risk, monoclonal antibodies blocking individual NIK-activating receptors are more cell-type and context specific

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Both nanoformulations induced cell death in both GBM cell lines (Fig