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Notably, metabolites such as AGEs, dysregulated ketone bodies, and BCAAs have been demonstrated to be directly or indirectly associated with structural abnormalities and functional decline in the lung (e.g., impaired surfactant synthesis, diminished respiratory muscle function)

Although we did not measure the ROS level directly, the above-described changes in SOD1 may suggest that the M-CFSs of both mushrooms have antioxidant properties in the HT-22 cell line

Sun Z, Huang Z, Zhang DD

Heme oxygenase-1 inhibits T cell-dependent skin inflammation and differentiation and function of antigen-presenting cells

4-Amino-5-methylamino-2,7-difluorofluorescein is a cell-permeable, NO-sensitive dye that is virtually nonfluorescent until it reacts with NO to form a fluorescent benzotriazole