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Neutrophil apoptosis is one of the essential mechanisms for maintaining homeostasis and limiting inflammatory damage

Cancer Res 76 , 45464558 (2016)

S12, the pGV469-mito-CD147 scFv adenoviral expression vector was constructed by cloning the matrix-targeting sequence (MTS, 5-ATGTCCGTCCTGACGCCGCTGCTGCTG CGGGGCTTGACAGGCTCGGCCCGGCGGCTCCCAGTGCCGCGCGCCAAGATCCATTCGTTG-3) of COX VIII and the scFv sequence of HAb18 57 , a monoclonal antibody targeting CD147, into the GV469 plasmid using Mlu I/Hind III, with EGFP fused at the C terminus