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Throughout the 3-month storage period, particle size measurements were conducted at defined intervals to observe any potential increase due to vesicle fusion or particle aggregation

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For the purposes of this article the two pathways will be discussed separately, but it should be appreciated that each pathway occurs within the same organelle so the possibility of crossover between them is real

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Conclusion: In summary, the results of the present study show that in FRTL cells, IGF-1 promotes cell cycle progression via an upregulation of cyclin D1 expression, at least partially through the PI3K/NF-B signaling pathway