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Description

A novel combined resveratrol/berberine phytochemotheraputic using the HePG2 cell line as a model for the treatment of hepatocarcinoma

A higher pre-drug urinary level of the compound taurine was associated with a lower degree of hepatotoxicity, whereas a higher pre-drug level of trimethylamine-N-oxide and betaine was associated with a greater severity of liver damage

The results showed that paraquat interfered with mitochondrial function for all parameters, and curcumin enhanced ATPassociated respiration

We also performed the trajectory analysis under the China/Asia-based control framework to evaluate the robustness of the inferred developmental changes observed in the primary analysis