melanotic hyperpigmentation

melanotic hyperpigmentation Oral Mucosal Melanosis Smoker's melanosis - Wikipedia

Name: melanotic hyperpigmentation Oral Mucosal Melanosis Smoker's melanosis - Wikipedia
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Smoker's melanosis Wikipedia Pigmented Lesions Springer Nature Link Riehl Melanosis MD Searchlight Hyperpigmentation Wikipedia Pigmented Lesions of the Oral Mucosa Pocket Dentistry

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RNA-seq transcriptomic analysis demonstrated significant dysregulation of immune-related pathways, accompanied by elevated pro-inflammatory cytokines (e.g., IL1B , TNF ) and decreased anti-inflammatory cytokines (e.g., IL4 , IL10 )

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doi: 10.3390/nu13093143 40 DubocHRajcaSRainteauDBenarousDMaubertMAQuervainEet al

however, persistent or dysregulated activation can drive neurodegeneration through inflammatory signaling, metabolic imbalance and synaptic disruption