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One or more flattened granulosa cells exist in the primary follicle, which surround the oocyte in one layer, and then deformed to a cubic structure and express FSH receptors, which indicates the beginning of primary follicle development

Transcriptomic analysis of C11orf54-knocked down and control cells demonstrated a marked inhibition of HIF1A signaling, which promoted HSC70 and HIF1A binding (114)

8,9 Women with polycystic ovary syndrome are at increased risk of high blood sugar, type 2 diabetes, and other changes that may increase cardiovascular disease risk

Liu Z, Zhao H, Liu W, Li T, Wang Y, Zhao M (2015) NLRP3 inflammasome activation is essential for paraquat-induced acute lung injury

Ascorbic acid is important as it is needed to maintain the health of skin, teeth, cartilage, bone and blood vessels