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Better workout endurance and recovery

If you're experiencing fatigue, weakness, or difficulty concentrating, you may benefit from B12 supplementation

Table 10: Efficacy Results of KEYNOTE-189 At the protocol specified final OS analysis, the median in the pemetrexed in combination with pembrolizumab and platinum chemotherapy arm was 22.0 months (95% CI: 19.5, 24.5) compared to 10.6 months (95% CI: 8.7, 13.6) in the placebo with pemetrexed and platinum chemotherapy arm, with an HR of 0.56 (95% CI: 0.46, 0.69)

The same is true if your blood work only shows signs of mild abnormalities: high levels of reticulocytes (immature red blood cells), homocysteine (an amino acid broken down by vitamin B12), or methylmalonic acid (MMA, a byproduct of amino acid breakdown) should subside after just a few vitamin B12 injection treatments

Because much of the evidence is preclinical, a provider will set an honest, individualized timeline and measure your response rather than promise a fixed number of weeks