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Excluding unknown indications, the most prevalent conditions treated with anakinra and canakinumab were RA (26.56%) and Stills disease (16.57%), respectively

This result suggests that glutathione sulfinamide could be metabolized into -Glu-3-sulfamoyl-Ala-Gly via an oxidative reaction

These findings confirm the functional loss of XKR8 in neutrophils from XKR8 KO mice and support its essential role in both apoptotic and NETosis-associated lipid scrambling

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