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Given the narrative nature of this review, a formal systematic approach or adherence to PRISMA guidelines was not employed, allowing for a more flexible and interpretive synthesis of the vast and heterogeneous literature on this topic

Kleinewietfeld et al

In addition, the tumor suppressor BAP1 decreases H2Aub occupancy on the SLC7A11 promoter and represses SLC7A11 expression in a deubiquitinating-dependent manner, that is, BAP1 inhibits cystine uptake by repressing SLC7A11 expression, leading to elevated lipid peroxidation and ferroptosis rates [54]

Rosolov, H., Simon, J., Mayer, O., Jr, Racek, J., Dierz, T., & Jacobsen, D

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