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A study in obese volunteers revealed that a ketogenic diet led to changes in the levels of microRNAs associated with antioxidant and anti-inflammatory signaling pathways, but these levels returned to normal after termination of the KD ( Compared to the expression profiles of mRNAs or miRNAs, lncRNAs are considered sensitive regulatory factors associated with HF and involve numerous regulatory pathways

i,j , the residual error of study i with j time

The chain-length-resolved acylcarnitine data revealed a pattern that contradicted the prevailing model: Why It Matters The chain-length pattern told a story that no single measurement could: short-chain species (C2, C4) were elevated because beta-oxidation was running at oull speed but the TCA cycle couldn't oxidize all the acetyl-CoA produced, causing incomplete oxidation and acylcarnitine "spillover." Meanwhile, long-chain species (C14, C16) were elevated because excess dietary lipid supply simply overloaded CPT-I import capacity

doi:10.1016/j.sleh.2021.05.004

The American Journal of Clinical Nutrition, 54 (6 Suppl), 1147S1152S