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Abstract Objective: Chronic sleep deprivation (CSD) is a major public health issue that causes metabolic dysfunction by disrupting redox homeostasis and triggering hepatic inflammation

10.3390/ijerph17197156 Int

Furthermore, loss of immunoreactivity to APE1 was observed in spinal cords of pre-symptomatic SOD1 G93A mice, suggesting that reduced levels of APE1 in motor neurons precede neurodegeneration (Manabe et al., 2001

Finally, the colon and bladder share several bacterial species in their microbiota, which may be an additional point of contact between these two organs