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Studies suggest that hypoxia causes the reduction of ATP synthesis and the generation of ROS damage cells, and then leads to the dysfunction of mitochondrial and the disorder of oxidative phosphorylation, resulting in ferroptosis in neurodegenerative disorders (Marques et al

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When methylation is impaired, it affects the production of serotonin, dopamine, and norepinephrine, which are essential for maintaining mood balance

10.1007/BF02147797 121 GodosJ.CurrentiW.AngelinoD.MenaP.CastellanoS.CaraciF.et al